The Transcription Factor LMO2 Is a Robust Marker of Vascular Endothelium and Vascular Neoplasms and Selected Other Entities

Image 6
Image 6

Nonvascular malignancies have LMO2+ vasculature, except hepatocellular carcinoma and a subset of clear cell renal cell carcinomas. A, B, and C, Lung adenocarcinoma (A, ×400), glioblastoma (B, ×400), and mesothelioma (C, ×400) have LMO2+ vasculature. D and E, Clear cell renal cell carcinomas may have LMO2+ (D, ×400) or LMO2– (E, ×400) vasculature. F, Hepatocellular carcinoma has LMO2– vasculature (arrows, LMO2– vessels; ×400).

This Article

  1. Am J Clin Pathol vol. 131 no. 2 264-278